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Thrombin Stimulates Increased PAI-1 Release from Liver Compared to Lung Endothelium
BACKGROUND: Plasminogen activator inhibitor-1 (PAI-1) is a major regulator of the fibrinolytic system, covalently binding to tissue plasminogen activator (tPA) and blocking its activity. Fibrinolysis shutdown is evident in the majority of severely injured patients in the first 24 hours and is though...
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| Publicado no: | J Surg Res |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5881926/ https://ncbi.nlm.nih.gov/pubmed/29605018 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jss.2017.12.017 |
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