28-day thawed plasma maintains α(2)-antiplasmin levels and inhibits tPA-induced fibrinolysis

INTRODUCTION: Evidence supports the use of plasma-first resuscitation in the treatment of trauma-induced coagulopathy (TIC). While thawed plasma (TP) has logistical benefits, the ability of plasma proteins to attenuate fibrinolysis and correct TIC remain unknown. We hypothesize that TP etains the ab...

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Pubblicato in:Vox Sang
Autori principali: Stettler, Gregory R., Moore, Ernest E., Huebner, Benjamin R., Nunns, Geoffrey R., Moore, Hunter B., Coleman, Julia R., Kelher, Marguerite, Banerjee, Anirban, Silliman, Christopher C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7962918/
https://ncbi.nlm.nih.gov/pubmed/32894784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/vox.12997
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