Pgam5 released from damaged mitochondria induces mitochondrial biogenesis via Wnt signaling

Mitochondrial abundance is dynamically regulated and was previously shown to be increased by Wnt/β-catenin signaling. Pgam5 is a mitochondrial phosphatase which is cleaved by the rhomboid protease presenilin-associated rhomboid-like protein (PARL) and released from membranes after mitochondrial stre...

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Bibliographic Details
Published in:J Cell Biol
Main Authors: Bernkopf, Dominic B., Jalal, Kowcee, Brückner, Martina, Knaup, Karl X., Gentzel, Marc, Schambony, Alexandra, Behrens, Jürgen
Format: Artigo
Language:Inglês
Published: Rockefeller University Press 2018
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5881504/
https://ncbi.nlm.nih.gov/pubmed/29438981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201708191
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