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Class IIa histone deacetylases link cAMP signaling to the myelin transcriptional program of Schwann cells
Schwann cells respond to cyclic adenosine monophosphate (cAMP) halting proliferation and expressing myelin proteins. Here we show that cAMP signaling induces the nuclear shuttling of the class IIa histone deacetylase (HDAC)–4 in these cells, where it binds to the promoter and blocks the expression o...
Tallennettuna:
| Julkaisussa: | J Cell Biol |
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| Päätekijät: | , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Rockefeller University Press
2018
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5881490/ https://ncbi.nlm.nih.gov/pubmed/29472387 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201611150 |
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