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Requirement of cAMP Signaling for Schwann Cell Differentiation Restricts the Onset of Myelination
Isolated Schwann cells (SCs) respond to cAMP elevation by adopting a differentiated post-mitotic state that exhibits high levels of Krox-20, a transcriptional enhancer of myelination, and mature SC markers such as the myelin lipid galactocerebroside (O1). To address how cAMP controls myelination, we...
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| Udgivet i: | PLoS One |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4338006/ https://ncbi.nlm.nih.gov/pubmed/25705874 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0116948 |
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