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Opposing Roles of pka and epac in the cAMP-Dependent Regulation of Schwann Cell Proliferation and Differentiation

In Schwann cells (SCs), cyclic adenosine monophosphate (cAMP) not only induces differentiation into a myelinating SC-related phenotype, but also synergistically enhances the mitogenic action of growth factors such as neuregulin. To better understand the molecular mechanism by which cAMP exerts these...

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Detalhes bibliográficos
Main Authors: Bacallao, Ketty, Monje, Paula V.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3859537/
https://ncbi.nlm.nih.gov/pubmed/24349260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0082354
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