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Class IIa histone deacetylases link cAMP signaling to the myelin transcriptional program of Schwann cells

Schwann cells respond to cyclic adenosine monophosphate (cAMP) halting proliferation and expressing myelin proteins. Here we show that cAMP signaling induces the nuclear shuttling of the class IIa histone deacetylase (HDAC)–4 in these cells, where it binds to the promoter and blocks the expression o...

詳細記述

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書誌詳細
出版年:J Cell Biol
主要な著者: Gomis-Coloma, Clara, Velasco-Aviles, Sergio, Gomez-Sanchez, Jose A., Casillas-Bajo, Angeles, Backs, Johannes, Cabedo, Hugo
フォーマット: Artigo
言語:Inglês
出版事項: Rockefeller University Press 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5881490/
https://ncbi.nlm.nih.gov/pubmed/29472387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201611150
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