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Class IIa histone deacetylases link cAMP signaling to the myelin transcriptional program of Schwann cells
Schwann cells respond to cyclic adenosine monophosphate (cAMP) halting proliferation and expressing myelin proteins. Here we show that cAMP signaling induces the nuclear shuttling of the class IIa histone deacetylase (HDAC)–4 in these cells, where it binds to the promoter and blocks the expression o...
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| 出版年: | J Cell Biol |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Rockefeller University Press
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5881490/ https://ncbi.nlm.nih.gov/pubmed/29472387 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201611150 |
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