A carregar...
TAK1ng control: TAK1 restrains NLRP3 activation
In this issue of JEM, Malireddi et al. (https://doi.org/10.1084/jem.20171922) demonstrate that macrophage-specific loss of TAK1 causes spontaneous NLRP3 inflammasome activation, driven by unregulated TNF secretion and signaling. This has implications for therapeutically targeting TAK1, enhancing its...
Na minha lista:
| Publicado no: | J Exp Med |
|---|---|
| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Rockefeller University Press
2018
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5881475/ https://ncbi.nlm.nih.gov/pubmed/29507056 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20180282 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|