A carregar...
TAK1 restricts spontaneous NLRP3 activation and cell death to control myeloid proliferation
The NOD-like receptor (NLR)–P3 inflammasome is a global sensor of infection and stress. Elevated NLRP3 activation levels are associated with human diseases, but the mechanisms controlling NLRP3 inflammasome activation are largely unknown. Here, we show that TGF-β activated kinase-1 (TAK1) is a centr...
Na minha lista:
| Publicado no: | J Exp Med |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Rockefeller University Press
2018
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5881469/ https://ncbi.nlm.nih.gov/pubmed/29500178 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20171922 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|