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Rab6-dependent retrograde traffic of LAT controls immune synapse formation and T cell activation
The adapter molecule linker for activation of T cells (LAT) orchestrates the formation of signalosomes upon T cell receptor (TCR) stimulation. LAT is present in different intracellular pools and is dynamically recruited to the immune synapse upon stimulation. However, the intracellular traffic of LA...
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| 出版年: | J Exp Med |
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| 主要な著者: | , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Rockefeller University Press
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5881459/ https://ncbi.nlm.nih.gov/pubmed/29440364 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20162042 |
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