Rab6-dependent retrograde traffic of LAT controls immune synapse formation and T cell activation

The adapter molecule linker for activation of T cells (LAT) orchestrates the formation of signalosomes upon T cell receptor (TCR) stimulation. LAT is present in different intracellular pools and is dynamically recruited to the immune synapse upon stimulation. However, the intracellular traffic of LA...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Carpier, Jean-Marie, Zucchetti, Andres E., Bataille, Laurence, Dogniaux, Stéphanie, Shafaq-Zadah, Massiullah, Bardin, Sabine, Lucchino, Marco, Maurin, Mathieu, Joannas, Leonel D., Magalhaes, Joao Gamelas, Johannes, Ludger, Galli, Thierry, Goud, Bruno, Hivroz, Claire
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2018
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5881459/
https://ncbi.nlm.nih.gov/pubmed/29440364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20162042
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