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Retrograde and Anterograde Transport of Lat-Vesicles during the Immunological Synapse Formation: Defining the Finely-Tuned Mechanism

LAT is an important player of the signaling cascade induced by TCR activation. This adapter molecule is present at the plasma membrane of T lymphocytes and more abundantly in intracellular compartments. Upon T cell activation the intracellular pool of LAT is recruited to the immune synapse (IS). We...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Saez, Juan José, Dogniaux, Stephanie, Shafaq-Zadah, Massiullah, Johannes, Ludger, Hivroz, Claire, Zucchetti, Andrés Ernesto
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7916135/
https://ncbi.nlm.nih.gov/pubmed/33572370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10020359
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