Tethering of vesicles to the Golgi by GMAP210 controls LAT delivery to the immune synapse

The T cell immune synapse is a site of intense vesicular trafficking. Here we show that the golgin GMAP210, known to capture vesicles and organize membrane traffic at the Golgi, is involved in the vesicular transport of LAT to the immune synapse. Upon activation, more GMAP210 interact with LAT-conta...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Zucchetti, Andres Ernesto, Bataille, Laurence, Carpier, Jean-Marie, Dogniaux, Stéphanie, San Roman-Jouve, Mabel, Maurin, Mathieu, Stuck, Michael W., Rios, Rosa M., Baldari, Cosima T., Pazour, Gregory J., Hivroz, Claire
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6599081/
https://ncbi.nlm.nih.gov/pubmed/31253807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10891-w
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