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The integrated stress response regulates BMP signalling through effects on translation

BACKGROUND: Developmental pathways must be responsive to the environment. Phosphorylation of eIF2α enables a family of stress-sensing kinases to trigger the integrated stress response (ISR), which has pro-survival and developmental consequences. Bone morphogenetic proteins (BMPs) regulate multiple d...

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Detalhes bibliográficos
Publicado no:BMC Biol
Main Authors: Malzer, Elke, Dominicus, Caia S., Chambers, Joseph E., Dickens, Jennifer A., Mookerjee, Souradip, Marciniak, Stefan J.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5881181/
https://ncbi.nlm.nih.gov/pubmed/29609607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-018-0503-x
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