Endoglin integrates BMP and Wnt signalling to induce haematopoiesis through JDP2

Mechanisms of haematopoietic and cardiac patterning remain poorly understood. Here we show that the BMP and Wnt signalling pathways are integrated in an endoglin (Eng)-dependent manner in cardiac and haematopoietic lineage specification. Eng is expressed in early mesoderm and marks both haematopoiet...

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Publicat a:Nat Commun
Autors principals: Baik, June, Magli, Alessandro, Tahara, Naoyuki, Swanson, Scott A., Koyano-Nakagawa, Naoko, Borges, Luciene, Stewart, Ron, Garry, Daniel J., Kawakami, Yasuhiko, Thomson, James A., Perlingeiro, Rita C. R.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5059784/
https://ncbi.nlm.nih.gov/pubmed/27713415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13101
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