Endoglin integrates BMP and Wnt signalling to induce haematopoiesis through JDP2

Mechanisms of haematopoietic and cardiac patterning remain poorly understood. Here we show that the BMP and Wnt signalling pathways are integrated in an endoglin (Eng)-dependent manner in cardiac and haematopoietic lineage specification. Eng is expressed in early mesoderm and marks both haematopoiet...

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Publicado en:Nat Commun
Autores principales: Baik, June, Magli, Alessandro, Tahara, Naoyuki, Swanson, Scott A., Koyano-Nakagawa, Naoko, Borges, Luciene, Stewart, Ron, Garry, Daniel J., Kawakami, Yasuhiko, Thomson, James A., Perlingeiro, Rita C. R.
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5059784/
https://ncbi.nlm.nih.gov/pubmed/27713415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13101
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