A critical role for endoglin in the emergence of blood during embryonic development

Much remains unknown about the signals that induce early mesoderm to initiate hematopoietic differentiation. Here, we show that endoglin (Eng), a receptor for the TGFβ superfamily, identifies all cells with hematopoietic fate in the early embryo. These arise in an Eng(+)Flk1(+) mesodermal precursor...

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Detaylı Bibliyografya
Asıl Yazarlar: Borges, Luciene, Iacovino, Michelina, Mayerhofer, Timothy, Koyano-Nakagawa, Naoko, Baik, June, Garry, Daniel J., Kyba, Michael, Letarte, Michelle, Perlingeiro, Rita C. R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Hematology 2012
Konular:
Hematopoiesis and Stem Cells
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3369678/
https://ncbi.nlm.nih.gov/pubmed/22535663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-11-391896
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