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Modulation of TGF-β signaling by endoglin in murine hemangioblast development and primitive hematopoiesis

Endoglin (Eng), an accessory receptor for the transforming growth factor β (TGF-β) superfamily, is required for proper hemangioblast and primitive hematopoietic development. However the mechanism by which endoglin functions at this early developmental stage is currently unknown. Transcriptional anal...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zhang, Liying, Magli, Alessandro, Catanese, Jacquelyn, Xu, Zhaohui, Kyba, Michael, Perlingeiro, Rita C. R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3139390/
https://ncbi.nlm.nih.gov/pubmed/21602526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-12-325019
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