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Structural basis of the Cope rearrangement and cyclization in hapalindole biogenesis
Hapalindole alkaloids are a structurally diverse class of cyanobacterial natural products defined by their varied polycyclic ring systems and diverse biological activities. These complex metabolites are generated from a common biosynthetic intermediate by the Stig cyclases in three mechanistic steps...
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| Publicat a: | Nat Chem Biol |
|---|---|
| Autors principals: | , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5880276/ https://ncbi.nlm.nih.gov/pubmed/29531360 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41589-018-0003-x |
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