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Structural basis of the Cope rearrangement and cyclization in hapalindole biogenesis
Hapalindole alkaloids are a structurally diverse class of cyanobacterial natural products defined by their varied polycyclic ring systems and diverse biological activities. These complex metabolites are generated from a common biosynthetic intermediate by the Stig cyclases in three mechanistic steps...
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| Pubblicato in: | Nat Chem Biol |
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| Autori principali: | , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5880276/ https://ncbi.nlm.nih.gov/pubmed/29531360 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41589-018-0003-x |
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