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Lanthanide-based T(2ex) and CEST complexes provide new insights into the design of pH sensitive MRI agents
A series of Eu(3+) and Dy(3+) DOTA-tetraamide complexes with four appended primary amine groups were prepared and their CEST and T(1)/T(2) relaxation properties measured as a function of pH. The CEST signals in the Eu(3+) complexes show a surprisingly strong CEST signal after the pH was reduced from...
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| Publicado no: | Angew Chem Int Ed Engl |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5879776/ https://ncbi.nlm.nih.gov/pubmed/29024242 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201707959 |
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