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Lanthanide-based T(2ex) and CEST complexes provide new insights into the design of pH sensitive MRI agents

A series of Eu(3+) and Dy(3+) DOTA-tetraamide complexes with four appended primary amine groups were prepared and their CEST and T(1)/T(2) relaxation properties measured as a function of pH. The CEST signals in the Eu(3+) complexes show a surprisingly strong CEST signal after the pH was reduced from...

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Dades bibliogràfiques
Publicat a:Angew Chem Int Ed Engl
Autors principals: Zhang, Lei, Martins, André F., Zhao, Piyu, Wu, Yunkou, Tircsó, Gyula, Sherry, A. Dean
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5879776/
https://ncbi.nlm.nih.gov/pubmed/29024242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201707959
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