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A Responsive Europium(III) Chelate that Provides a Direct Readout of pH by MRI

[Image: see text] A europium(III) DO3A-tris(amide) complex is reported for imaging pH by MRI using ratiometric CEST principles. Deprotonation of a single phenolic proton between pH 6 and 7.6 results in an ~5 ppm shift in the water exchange CEST peak that is easily detected by MRI. Collection of two...

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Detalhes bibliográficos
Main Authors: Wu, Yunkou, Soesbe, Todd C., Kiefer, Garry E., Zhao, Piyu, Sherry, A. Dean
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2951490/
https://ncbi.nlm.nih.gov/pubmed/20853833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja106018n
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