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A Novel Class of Polymeric pH-Responsive MRI CEST Agents

In this communication, we report that ionizable, tertiary amine-based block copolymers can be used as pH-responsive contrast agents for magnetic resonance imaging (MRI) through the chemical exchange saturation transfer (CEST) mechanism. The CEST signal is essentially “off” when the polymers form mic...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zhang, Shanrong, Zhou, Kejin, Huang, Gang, Takahashi, Masaya, Sherry, A. Dean, Gao, Jinming
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3712501/
https://ncbi.nlm.nih.gov/pubmed/23752496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3cc42452a
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