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pH imaging of mouse kidneys in vivo using a frequency-dependent paraCEST agent

PURPOSE: This study explored the feasibility of using a pH responsive paraCEST agent to image the pH gradient in kidneys of healthy mice. METHODS: CEST signals were acquired on an Agilent 9.4 T small animal MRI system using a steady-state gradient echo pulse sequence after a bolus injection of agent...

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Bibliografische gegevens
Gepubliceerd in:Magn Reson Med
Hoofdauteurs: Wu, Yunkou, Zhang, Shanrong, Soesbe, Todd C., Yu, Jing, Vinogradov, Elena, Lenkinski, Robert E., Sherry, A. Dean
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4713392/
https://ncbi.nlm.nih.gov/pubmed/26173637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mrm.25844
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