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Resolving the Role of Lipoxygenases in the Initiation and Execution of Ferroptosis

[Image: see text] Lipoxygenases (LOXs) have been implicated as central players in ferroptosis, a recently characterized cell death modality associated with the accumulation of lipid hydroperoxides: the products of LOX catalysis. To provide insight on their role, human embryonic kidney cells were tra...

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Pubblicato in:ACS Cent Sci
Autori principali: Shah, Ron, Shchepinov, Mikhail S., Pratt, Derek A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2018
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5879472/
https://ncbi.nlm.nih.gov/pubmed/29632885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscentsci.7b00589
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