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Endolysosomal pathway activity protects cells from neurotoxic TDP-43
The accumulation of protein aggregates in neurons is a typical pathological hallmark of the motor neuron disease amyotrophic lateral sclerosis (ALS) and of frontotemporal dementia (FTD). In many cases, these aggregates are composed of the 43 kDa TAR DNA-binding protein (TDP 43). Using a yeast model...
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| Publicat a: | Microb Cell |
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| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Shared Science Publishers OG
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5878689/ https://ncbi.nlm.nih.gov/pubmed/29611555 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15698/mic2018.04.627 |
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