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Phosphorylation Modulates Aspartyl-(Asparaginyl)-β Hydroxylase Protein Expression, Catalytic Activity and Migration in Human Immature Neuronal Cerebellar Cells

BACKGROUND: Abundant aspartyl-asparaginyl-β-hydroxylase (ASPH) expression supports robust neuronal migration during development, and reduced ASPH expression and function, as occur in fetal alcohol spectrum disorder, impair cerebellar neuron migration. ASPH mediates its effects on cell migration via...

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Détails bibliographiques
Publié dans:Cell Biol (Henderson, NV)
Auteurs principaux: Tong, Ming, Gao, Jin-Song, Borgas, Diana, de la Monte, Suzanne M.
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5878085/
https://ncbi.nlm.nih.gov/pubmed/29607347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/2324-9293.1000133
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