Prediction of Tacrolimus Exposure by CYP3A5 Genotype and Exposure of Co-Administered Everolimus in Japanese Renal Transplant Recipients

While tacrolimus and everolimus have common metabolic pathways through CYP3A4/5, tacrolimus is metabolized solely by CYP3A4 in recipients with the CYP3A5*3/*3. The purpose of this study was to evaluate how the area under the blood concentration-time curves (AUC) of tacrolimus could be predicted base...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Int J Mol Sci
Hoofdauteurs: Kagaya, Hideaki, Niioka, Takenori, Saito, Mitsuru, Inoue, Takamitsu, Numakura, Kazuyuki, Yamamoto, Ryohei, Akamine, Yumiko, Habuchi, Tomonori, Satoh, Shigeru, Miura, Masatomo
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2018
Onderwerpen:
Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5877743/
https://ncbi.nlm.nih.gov/pubmed/29547545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19030882
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items