Prediction of Tacrolimus Exposure by CYP3A5 Genotype and Exposure of Co-Administered Everolimus in Japanese Renal Transplant Recipients

While tacrolimus and everolimus have common metabolic pathways through CYP3A4/5, tacrolimus is metabolized solely by CYP3A4 in recipients with the CYP3A5*3/*3. The purpose of this study was to evaluate how the area under the blood concentration-time curves (AUC) of tacrolimus could be predicted base...

Full description

Saved in:
Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Kagaya, Hideaki, Niioka, Takenori, Saito, Mitsuru, Inoue, Takamitsu, Numakura, Kazuyuki, Yamamoto, Ryohei, Akamine, Yumiko, Habuchi, Tomonori, Satoh, Shigeru, Miura, Masatomo
Format: Artigo
Language:Inglês
Published: MDPI 2018
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5877743/
https://ncbi.nlm.nih.gov/pubmed/29547545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19030882
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items