Influence of NAT2 Polymorphisms on Sulfamethoxazole Pharmacokinetics in Renal Transplant Recipients

The sulfamethoxazole (SMX)-trimethoprim drug combination is routinely used as prophylaxis against Pneumocystis pneumonia during the first 3 to 6 months after renal transplantation. The objective of this study was to examine the impact of N-acetyltransferase 2 (NAT2) and CYP2C9 polymorphisms on the p...

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Bibliographic Details
Main Authors: Kagaya, Hideaki, Miura, Masatomo, Niioka, Takenori, Saito, Mitsuru, Numakura, Kazuyuki, Habuchi, Tomonori, Satoh, Shigeru
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2012
Subjects:
Pharmacology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3264276/
https://ncbi.nlm.nih.gov/pubmed/22106207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05037-11
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