Clinical implications of pharmacokinetics of sunitinib malate and N-desethyl-sunitinib plasma concentrations for treatment outcome in metastatic renal cell carcinoma patients

In this study, we examined the association between the pharmacokinetics (PK) level of sunitinib malate (SU) and its metabolite N-desethyl-sunitinib (DSU) in terms of adverse events (AEs) and clinical outcomes in patients with metastatic renal cell carcinoma (mRCC). The PK of sunitinib (SU and DSU) w...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Oncotarget
Egile Nagusiak: Numakura, Kazuyuki, Fujiyama, Nobuhiro, Takahashi, Makoto, Igarashi, Ryoma, Tsuruta, Hiroshi, Maeno, Atsushi, Huang, Mingguo, Saito, Mitsuru, Narita, Shintaro, Inoue, Takamitsu, Satoh, Shigeru, Tsuchiya, Norihiko, Niioka, Takenori, Miura, Masatomo, Habuchi, Tomonori
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Impact Journals LLC 2018
Gaiak:
Research Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5982748/
https://ncbi.nlm.nih.gov/pubmed/29861870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25423
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