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Interaction between rpsL and gyrA mutations affects the fitness and dual resistance of Mycobacterium tuberculosis clinical isolates against streptomycin and fluoroquinolones

BACKGROUND: The interaction between different drug-resistant mutations is important to the development of drug resistance and its evolution. In this study, we aimed to reveal the potential relationships between mutations conferring resistance to two important antituberculosis drugs streptomycin (STR...

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Publicat a:Infect Drug Resist
Autors principals: Sun, Honghu, Zeng, Jumei, Li, Song, Liang, Pengkuan, Zheng, Chao, Liu, Yong, Luo, Tao, Rastogi, Nalin, Sun, Qun
Format: Artigo
Idioma:Inglês
Publicat: SAGE Publications 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5877491/
https://ncbi.nlm.nih.gov/pubmed/29628767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IDR.S152335
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