Interaction between rpsL and gyrA mutations affects the fitness and dual resistance of Mycobacterium tuberculosis clinical isolates against streptomycin and fluoroquinolones

BACKGROUND: The interaction between different drug-resistant mutations is important to the development of drug resistance and its evolution. In this study, we aimed to reveal the potential relationships between mutations conferring resistance to two important antituberculosis drugs streptomycin (STR...

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Detalhes bibliográficos
Publicado no:Infect Drug Resist
Main Authors: Sun, Honghu, Zeng, Jumei, Li, Song, Liang, Pengkuan, Zheng, Chao, Liu, Yong, Luo, Tao, Rastogi, Nalin, Sun, Qun
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2018
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5877491/
https://ncbi.nlm.nih.gov/pubmed/29628767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IDR.S152335
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