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Mutations in gyrA and gyrB among Fluoroquinolone- and Multidrug-Resistant Mycobacterium tuberculosis Isolates

In order to correlate the mutations inside the entire gyrA and gyrB genes with the level of resistance to ofloxacin (OFX) and moxifloxacin (MFX) in isolates of multidrug-resistant Mycobacterium tuberculosis (MDR-TB), a total of 111 isolates were categorized into OFX-susceptible (MIC, ≤2 μg/ml) and l...

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Publicado en:Antimicrob Agents Chemother
Autores principales: Chien, Jung-Yien, Chiu, Wei-Yih, Chien, Shun-Tien, Chiang, Chia-Jung, Yu, Chong-Jen, Hsueh, Po-Ren
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4808166/
https://ncbi.nlm.nih.gov/pubmed/26787695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01049-15
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