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The Fitness Cost of Streptomycin Resistance Depends on rpsL Mutation, Carbon Source and RpoS (σ(S))

Mutations that cause antibiotic resistance often produce associated fitness costs. These costs have a detrimental effect on the fate of resistant organisms in natural populations and could be exploited in designing drugs, therapeutic regimes, and intervention strategies. The streptomycin resistance...

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Detalhes bibliográficos
Main Authors: Paulander, Wilhelm, Maisnier-Patin, Sophie, Andersson, Dan I.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2766315/
https://ncbi.nlm.nih.gov/pubmed/19652179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.109.106104
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