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Amplification of the Gene for Isoleucyl–tRNA Synthetase Facilitates Adaptation to the Fitness Cost of Mupirocin Resistance in Salmonella enterica

Mutations that cause resistance to antibiotics in bacteria often reduce growth rate by impairing some essential cellular function. This growth impairment is expected to counterselect resistant organisms from natural populations following discontinuation of antibiotic therapy. Unfortunately (for dise...

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Detalhes bibliográficos
Main Authors: Paulander, Wilhelm, Andersson, Dan I., Maisnier-Patin, Sophie
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2870965/
https://ncbi.nlm.nih.gov/pubmed/20176977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.109.113514
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