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Amplification of the Gene for Isoleucyl–tRNA Synthetase Facilitates Adaptation to the Fitness Cost of Mupirocin Resistance in Salmonella enterica

Mutations that cause resistance to antibiotics in bacteria often reduce growth rate by impairing some essential cellular function. This growth impairment is expected to counterselect resistant organisms from natural populations following discontinuation of antibiotic therapy. Unfortunately (for dise...

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書誌詳細
主要な著者: Paulander, Wilhelm, Andersson, Dan I., Maisnier-Patin, Sophie
フォーマット: Artigo
言語:Inglês
出版事項: Genetics Society of America 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2870965/
https://ncbi.nlm.nih.gov/pubmed/20176977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.109.113514
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