Full-length mRNA sequencing uncovers a widespread coupling between transcription initiation and mRNA processing

BACKGROUND: The multifaceted control of gene expression requires tight coordination of regulatory mechanisms at transcriptional and post-transcriptional level. Here, we studied the interdependence of transcription initiation, splicing and polyadenylation events on single mRNA molecules by full-lengt...

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Bibliografiske detaljer
Udgivet i:Genome Biol
Main Authors: Anvar, Seyed Yahya, Allard, Guy, Tseng, Elizabeth, Sheynkman, Gloria M., de Klerk, Eleonora, Vermaat, Martijn, Yin, Raymund H., Johansson, Hans E., Ariyurek, Yavuz, den Dunnen, Johan T., Turner, Stephen W., ‘t Hoen, Peter A. C.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2018
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5877393/
https://ncbi.nlm.nih.gov/pubmed/29598823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-018-1418-0
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