Full-length mRNA sequencing uncovers a widespread coupling between transcription initiation and mRNA processing

BACKGROUND: The multifaceted control of gene expression requires tight coordination of regulatory mechanisms at transcriptional and post-transcriptional level. Here, we studied the interdependence of transcription initiation, splicing and polyadenylation events on single mRNA molecules by full-lengt...

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Dettagli Bibliografici
Pubblicato in:Genome Biol
Autori principali: Anvar, Seyed Yahya, Allard, Guy, Tseng, Elizabeth, Sheynkman, Gloria M., de Klerk, Eleonora, Vermaat, Martijn, Yin, Raymund H., Johansson, Hans E., Ariyurek, Yavuz, den Dunnen, Johan T., Turner, Stephen W., ‘t Hoen, Peter A. C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2018
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5877393/
https://ncbi.nlm.nih.gov/pubmed/29598823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-018-1418-0
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