Full-length mRNA sequencing uncovers a widespread coupling between transcription initiation and mRNA processing

BACKGROUND: The multifaceted control of gene expression requires tight coordination of regulatory mechanisms at transcriptional and post-transcriptional level. Here, we studied the interdependence of transcription initiation, splicing and polyadenylation events on single mRNA molecules by full-lengt...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Genome Biol
Main Authors: Anvar, Seyed Yahya, Allard, Guy, Tseng, Elizabeth, Sheynkman, Gloria M., de Klerk, Eleonora, Vermaat, Martijn, Yin, Raymund H., Johansson, Hans E., Ariyurek, Yavuz, den Dunnen, Johan T., Turner, Stephen W., ‘t Hoen, Peter A. C.
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2018
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5877393/
https://ncbi.nlm.nih.gov/pubmed/29598823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-018-1418-0
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