Full-length mRNA sequencing uncovers a widespread coupling between transcription initiation and mRNA processing

BACKGROUND: The multifaceted control of gene expression requires tight coordination of regulatory mechanisms at transcriptional and post-transcriptional level. Here, we studied the interdependence of transcription initiation, splicing and polyadenylation events on single mRNA molecules by full-lengt...

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Veröffentlicht in:Genome Biol
Hauptverfasser: Anvar, Seyed Yahya, Allard, Guy, Tseng, Elizabeth, Sheynkman, Gloria M., de Klerk, Eleonora, Vermaat, Martijn, Yin, Raymund H., Johansson, Hans E., Ariyurek, Yavuz, den Dunnen, Johan T., Turner, Stephen W., ‘t Hoen, Peter A. C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2018
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5877393/
https://ncbi.nlm.nih.gov/pubmed/29598823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-018-1418-0
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