CTCF Binding Sites in the Herpes Simplex Virus 1 Genome Display Site-Specific CTCF Occupation, Protein Recruitment, and Insulator Function

There are seven conserved CTCF binding domains in the herpes simplex virus 1 (HSV-1) genome. These binding sites individually flank the latency-associated transcript (LAT) and the immediate early (IE) gene regions, suggesting that CTCF insulators differentially control transcriptional domains in HSV...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Washington, Shannan D., Musarrat, Farhana, Ertel, Monica K., Backes, Gregory L., Neumann, Donna M.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2018
Sujets:
Genome Replication and Regulation of Viral Gene Expression
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5874429/
https://ncbi.nlm.nih.gov/pubmed/29437965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00156-18
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