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Culture-independent discovery of the malacidins as calcium-dependent antibiotics with activity against multidrug-resistant Gram-positive pathogens
Despite the wide availability of antibiotics, infectious diseases remain a leading cause of death worldwide.(1) In the absence of new therapies, mortality rates due to untreatable infections are predicted to rise more than 10-fold by 2050. Natural products (NPs) made by cultured bacteria have been a...
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| Veröffentlicht in: | Nat Microbiol |
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| Hauptverfasser: | , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5874163/ https://ncbi.nlm.nih.gov/pubmed/29434326 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41564-018-0110-1 |
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