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Cellular tolerance at the µ-opioid receptor is phosphorylation dependent
Phosphorylation of the μ-opioid receptor (MOR) is known as a key step in desensitization and internalization but the role in the development of long-term tolerance at the cellular level is not known. Viral expression of wild type (exWT) and mutant MORs, where all phosphorylation sites on the C-termi...
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| Publicado en: | eLife |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
eLife Sciences Publications, Ltd
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5873894/ https://ncbi.nlm.nih.gov/pubmed/29589831 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.34989 |
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