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Platelet HMGB1 is required for efficient bacterial clearance in intra-abdominal bacterial sepsis in mice
Thrombocytopenia impairs host defense and hemostasis in sepsis. However, the mechanisms of how platelets regulate host defense are not fully understood. High-mobility group box 1 (HMGB1), a danger-associated molecular pattern protein, is released during infection and contributes to the pathogenesis...
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| 出版年: | Blood Adv |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society of Hematology
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5873229/ https://ncbi.nlm.nih.gov/pubmed/29563120 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2017011817 |
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