Elevated polygenic burden for autism is associated with differential DNA methylation at birth

BACKGROUND: Autism spectrum disorder (ASD) is a severe neurodevelopmental disorder characterized by deficits in social communication and restricted, repetitive behaviors, interests, or activities. The etiology of ASD involves both inherited and environmental risk factors, with epigenetic processes h...

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Published in:Genome Med
Main Authors: Hannon, Eilis, Schendel, Diana, Ladd-Acosta, Christine, Grove, Jakob, Hansen, Christine Søholm, Andrews, Shan V., Hougaard, David Michael, Bresnahan, Michaeline, Mors, Ole, Hollegaard, Mads Vilhelm, Bækvad-Hansen, Marie, Hornig, Mady, Mortensen, Preben Bo, Børglum, Anders D., Werge, Thomas, Pedersen, Marianne Giørtz, Nordentoft, Merete, Buxbaum, Joseph, Daniele Fallin, M., Bybjerg-Grauholm, Jonas, Reichenberg, Abraham, Mill, Jonathan
Format: Artigo
Language:Inglês
Published: BioMed Central 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5872584/
https://ncbi.nlm.nih.gov/pubmed/29587883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-018-0527-4
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