Elevated polygenic burden for autism is associated with differential DNA methylation at birth

BACKGROUND: Autism spectrum disorder (ASD) is a severe neurodevelopmental disorder characterized by deficits in social communication and restricted, repetitive behaviors, interests, or activities. The etiology of ASD involves both inherited and environmental risk factors, with epigenetic processes h...

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Bibliografski detalji
Izdano u:Genome Med
Glavni autori: Hannon, Eilis, Schendel, Diana, Ladd-Acosta, Christine, Grove, Jakob, Hansen, Christine Søholm, Andrews, Shan V., Hougaard, David Michael, Bresnahan, Michaeline, Mors, Ole, Hollegaard, Mads Vilhelm, Bækvad-Hansen, Marie, Hornig, Mady, Mortensen, Preben Bo, Børglum, Anders D., Werge, Thomas, Pedersen, Marianne Giørtz, Nordentoft, Merete, Buxbaum, Joseph, Daniele Fallin, M., Bybjerg-Grauholm, Jonas, Reichenberg, Abraham, Mill, Jonathan
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2018
Teme:
Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5872584/
https://ncbi.nlm.nih.gov/pubmed/29587883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-018-0527-4
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