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Elevated polygenic burden for autism is associated with differential DNA methylation at birth

BACKGROUND: Autism spectrum disorder (ASD) is a severe neurodevelopmental disorder characterized by deficits in social communication and restricted, repetitive behaviors, interests, or activities. The etiology of ASD involves both inherited and environmental risk factors, with epigenetic processes h...

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Bibliografiset tiedot
Julkaisussa:Genome Med
Päätekijät: Hannon, Eilis, Schendel, Diana, Ladd-Acosta, Christine, Grove, Jakob, Hansen, Christine Søholm, Andrews, Shan V., Hougaard, David Michael, Bresnahan, Michaeline, Mors, Ole, Hollegaard, Mads Vilhelm, Bækvad-Hansen, Marie, Hornig, Mady, Mortensen, Preben Bo, Børglum, Anders D., Werge, Thomas, Pedersen, Marianne Giørtz, Nordentoft, Merete, Buxbaum, Joseph, Daniele Fallin, M., Bybjerg-Grauholm, Jonas, Reichenberg, Abraham, Mill, Jonathan
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5872584/
https://ncbi.nlm.nih.gov/pubmed/29587883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-018-0527-4
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