Elevated polygenic burden for autism is associated with differential DNA methylation at birth

BACKGROUND: Autism spectrum disorder (ASD) is a severe neurodevelopmental disorder characterized by deficits in social communication and restricted, repetitive behaviors, interests, or activities. The etiology of ASD involves both inherited and environmental risk factors, with epigenetic processes h...

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Detalhes bibliográficos
Publicado no:Genome Med
Main Authors: Hannon, Eilis, Schendel, Diana, Ladd-Acosta, Christine, Grove, Jakob, Hansen, Christine Søholm, Andrews, Shan V., Hougaard, David Michael, Bresnahan, Michaeline, Mors, Ole, Hollegaard, Mads Vilhelm, Bækvad-Hansen, Marie, Hornig, Mady, Mortensen, Preben Bo, Børglum, Anders D., Werge, Thomas, Pedersen, Marianne Giørtz, Nordentoft, Merete, Buxbaum, Joseph, Daniele Fallin, M., Bybjerg-Grauholm, Jonas, Reichenberg, Abraham, Mill, Jonathan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5872584/
https://ncbi.nlm.nih.gov/pubmed/29587883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-018-0527-4
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