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Ethylatropine Bromide as a Peripherally Restricted Muscarinic Antagonist

Quaternary ammonium analogues of atropine that are unable to cross the blood-brain barrier are used to alleviate peripheral muscarinic toxicity in animal models of epilepsy produced by systemic administration of pilocarpine or diisopropylfluorophosphate (DFP). Currently, methylatropine is the most p...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:ACS Chem Neurosci
Prif Awduron: Rojas, Asheebo, Ganesh, Thota, Walker, Alec, Dingledine, Raymond
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5872150/
https://ncbi.nlm.nih.gov/pubmed/28044440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.6b00334
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