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Spatially localized generation of nucleotide sequence-specific DNA damage

Psoralens linked to triplex-forming oligonucleotides (psoTFOs) have been used in conjunction with laser-induced two-photon excitation (TPE) to damage a specific DNA target sequence. To demonstrate that TPE can initiate photochemistry resulting in psoralen–DNA photoadducts, target DNA sequences were...

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Hlavní autoři: Oh, Dennis H., King, Brett A., Boxer, Steven G., Hanawalt, Philip C.
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences 2001
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC58719/
https://ncbi.nlm.nih.gov/pubmed/11572980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.201409698
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