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Nucleotide-Specific Contrast for DNA Sequencing by Electron Spectroscopy

DNA sequencing by imaging in an electron microscope is an approach that holds promise to deliver long reads with low error rates and without the need for amplification. Earlier work using transmission electron microscopes, which use high electron energies on the order of 100 keV, has shown that low...

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Bibliographic Details
Published in:PLoS One
Main Authors: Mankos, Marian, Persson, Henrik H. J., N’Diaye, Alpha T., Shadman, Khashayar, Schmid, Andreas K., Davis, Ronald W.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4858156/
https://ncbi.nlm.nih.gov/pubmed/27149617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0154707
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