Virtual Terminator nucleotides for next generation DNA sequencing

We synthesized reversible terminators with tethered inhibitors for next generation sequencing. These were efficiently incorporated with high fidelity while preventing incorporation of additional nucleotides and were used to sequence canine bacterial artificial chromosomes in a single-molecule system...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Bowers, Jayson, Mitchell, Judith, Beer, Eric, Buzby, Philip R., Causey, Marie, Efcavitch, J. William, Jarosz, Mirna, Krzymanska-Olejnik, Edyta, Kung, Li, Lipson, Doron, Lowman, Geoffrey M., Marappan, Subramanian, McInerney, Peter, Platt, Adam, Roy, Atanu, Siddiqi, Suhaib M., Steinmann, Kathleen, Thompson, John F.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2009
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2719685/
https://ncbi.nlm.nih.gov/pubmed/19620973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.1354
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